Two-way ANOVA analysis showed a trend of higher increase of LV internal diameters and thickening of the interventricular septal wall in 5-HT 2B cTG mice, indicative of cardiac dilation and hypertrophy.
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The serotonin receptor 2b (5-HT<sub>2B</sub>) modulates heart remodeling following myocardial infarction via regulation of Hippo pathway.
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