Temporal Proteomic and Phosphoproteomic Profiling Deciphers Molecular Dynamics of Acute-to-Chronic Kidney Disease After Ischemia-Reperfusion Injury, With Dock2 Emerging as a Key Regulator.

Statistical analysis for the Δ exp and Δ phosph (normalized) indicated that the increase in Dock2 protein was significant at 7 days and 28 days post-IRI, whereas its normalized phosphorylation at S1704 did not reach statistical significance (ANOVA, p > 0.05), as detailed in Supplemental Figure S6 .

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