Serum neurofilament light chain and disease-modifying treatment as predictors of cognitive decline in multiple sclerosis.

Front Neurol · 2026 · PMC12915334 · PMID 41716551

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0690

boldest claim

The sentences

a trend toward significancep = 0.059so close (0.05 < p ≤ 0.1)

PwMS who showed a longitudinal decline in SDMT scores had higher log-transformed sNfL2 Z-scores compared to those, whose SDMT remained stable or improved (a trend toward significance, p = 0.059).

also in 1,840 other papers

showed a trendp = 0.069so close (0.05 < p ≤ 0.1)

At follow-up, the scores of PwMS decreased significantly (SDMT change −1.87 ± 6.35, p = 0.024), while CG showed a trend toward performing better the second time (+4.00 ± 8.28, p = 0.069).

also in 24,539 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.