Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB): A Translational Pharmacodynamic Biomarker for PIKfyve Inhibition With VRG50635.

Clin Transl Sci · 2026 · PMC12916242 · PMID 41708347

Europe PMC DOI

hedged sentence

0.0599

closest p · 1.2× alpha

0.0599

boldest claim

The sentences

showed a trendp value = 0.0599so close (0.05 < p ≤ 0.1)

The correlation between Gpnmb expression in the brain and VRG50468 plasma concentrations showed a trend ( p value = 0.0599) (Figures S4 and S5 ).

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