Intratumoral preservation of the stem-like malignant cell proportion in glioblastoma, prognostic impact, and its radiomethylomic signatures.

Compared to non-stem-like tumors, stem-like tumors showed a tendency toward lower distributional frequency in the frontal lobe and higher frequency in the parietal lobe, although these differences did not reach statistical significance (frontal lobe, 18% in stem-like tumors vs. 30% in non-stem-like tumors, P = .15; parietal lobe, 21% in stem-like tumors vs. 12% in non-stem-like tumors, P = .23) ( Figure 4A and B ).

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