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Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson's disease.

iScience · 2026 · PMC12918236 · PMID 41727181

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Genes that did not reach statistical significance (p.adj <0.05) or had low overall expression (BaseMean <200) were excluded, and fetal ventral and dorsal markers were defined as those with an absolute log 2 -fold-change greater than 3.

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