High burden of viridans streptococcal endocarditis linked to multidrug resistance and regional risk factors: a molecular epidemiological report from Khyber Pakhtunkhwa, Pakistan.

The only factor approaching significance was limited access to dental care ( p = 0.05), suggesting a potential but not definitive relationship.

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Limited access to dental care showed borderline significance (aOR = 2.10; 95% CI: 1.01–4.38; p = 0.05), whereas other variables such as prosthetic heart valves 9(aOR = 2.05, 95% CI: 0.74–5.67) and prior antibiotic use aOR = 1.35, 95% CI: 0.64–2.86) had elevated point estimates but did not remain significant after adjustment.

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Despite this, prosthetic valve implantation (aOR = 2.05, 95% CI: 0.74–5.67) and prior antibiotic use (aOR = 1.35, 95% CI: 0.64–2.86) continued to demonstrate high, though limited access to dental care was marginally significant (aOR = 2.10, 95% CI: 1.01–4.38, p = 0.05) (Table 7 ).

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