Association of active fluid de-escalation timing with clinical outcomes in patients with septic shock: a multicenter cohort study.

BMC Infect Dis · 2026 · PMC12918465 · PMID 41593444

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did not reach statistical significanceno p-value reported

Our analysis revealed that early de-escalation was associated with reduced 28-day mortality across multiple subgroups, though this protective association did not reach statistical significance in the AKI subgroup.

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