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Physiology-Guided Coronary Revascularization Versus Angiography in Chronic Coronary Syndromes: A Systematic Review of Major Adverse Cardiovascular Events.

Cureus · 2026 · PMC12923173 · PMID 41728560

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did not reach statistical significanceP = 0.08so close (0.05 < p ≤ 0.1)
22.4%), although this difference did not reach statistical significance (P = 0.08) [ 18 ]. van Nunen et al. reported that by five-year follow-up, MACE rates converged, with no statistically significant difference between strategies (28% vs. 31%, P = 0.31) [ 19 ].

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