Barely Significant
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Glymphatic system impairment in type II diabetes mellitus adults.

Sci Rep · 2026 · PMC12923780 · PMID 41639148

Europe PMCDOI
2
hedged sentences
0.1400
closest p · 2.8× alpha
0.1400
boldest claim

The sentences

a negative trendp = 0.14not close (p > 0.1)
A negative trend was observed between the DTI-ALPS indices and disease duration ( r = −0.17, p = 0.14) using Pearson’s correlation in T2DM adults (Supplementary Material, Tables S3).

also in 1,766 other papers

a decreasing trendno p-value reported
The animal model of T2DM showed a decreasing trend in aquaporin-4 expression with increased disease severity of the condition, which indicates a similar mechanism may underlie glymphatic dysfunction in T2DM patients and suggests that consideration of the aquaporin-4 water channel is crucial for assessment of the glymphatic system status.

also in 24,192 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.