Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced Hand Arthralgia in Breast Cancer Patients: A Systematic Review.

28 An 8-week Pilates program achieved a medium-to-large effect on functional performance (η 2 = 0.45), though between-group differences did not reach statistical significance. 29 A self-directed 6-week walking program also demonstrated significant improvements in WOMAC function and stiffness subscales ( P = .024 and P = .043, respectively), 31 indicating moderate enhancement of mobility and daily activity tolerance.

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