Urinary 8-hydroxy-2'-deoxyguanosine as an early predictive biomarker for glomerular filtration rate decline in patients with type 2 diabetes mellitus.

BMC Endocr Disord · 2026 · PMC12924210 · PMID 41606764

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0.1840

closest p · 3.7× alpha

0.1840

boldest claim

The sentences

did not reach statistical significanceP = 0.184not close (p > 0.1)

Notably, the association appeared stronger in patients with diabetes duration ≥ 10 years (HR: 4.16, 95% CI: 2.34–7.39) compared to those with shorter duration (HR: 2.87, 95% CI: 1.42–5.81), although the interaction did not reach statistical significance ( P = 0.184).

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