Where did I leave my systematic review protocol, and what should it contain regarding Trial Sequential Analysis?

BMC Med Res Methodol · 2026 · PMC12924246 · PMID 41612198

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did not reach statistical significanceno p-value reported

In unpaired comparisons, trends suggested that protocol-based reviews reported variance, power, and heterogeneity more frequently than those without protocol information, although these differences did not reach statistical significance.

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