Evaluation of 6-hour urine creatinine clearance as the kidney component in the SOFA score: An observational cohort study.

J Intensive Med · 2026 · PMC12925903 · PMID 41736786

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did not reach statistical significanceno p-value reported

A modified SOFA score (SOFA CrCl ), incorporating the categorical CrCl 6h , was also found to be a better predictor of ICU and 90-day mortality than the original SOFA score, although the difference did not reach statistical significance on all days examined.

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a trend toward significanceno p-value reported

Regarding ICU mortality, the AUROC value for CrCl 6h exceeded that for Scr by 7%–10%; this difference was significant on day 1, 2, and 3, while a trend toward significance was noted on day 4 and 5.

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