Fiber-2, not Fiber-1, is the principal protective immunogen of fowl adenovirus serotype 4: insights from a comparative efficacy study of chimeric virus-based inactivated vaccines.

Although statistical difference between the two vaccine groups was not significant across all time points, the rFAdV-4-Δfiber1-fiber/8b group showed a trend toward earlier clearance, with shedding limited to days 1 and 2, whereas low-level shedding persisted slightly longer in some birds from the rFAdV-4-Δfiber2-fiber/8b group.

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