The Role of HER2 and RANK in Breast Cancer and New Therapeutic Approaches With Denosumab, Anti-HER2 Antibodies and Immunotherapy.

J Cell Mol Med · 2026 · PMC12929656 · PMID 41731687

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.090so close (0.05 < p ≤ 0.1)

A similar trend was observed concerning HER2 status and ER expression, although this correlation did not reach statistical significance ( p = 0.090).

also in 111,027 other papers

highly significantno p-value reported

Notably, co‐expression patterns of progesterone receptor (PR) and oestrogen receptor (ER) were identified, with a Chi‐Square analysis yielding a p ‐value of < 0.001, indicating a highly significant association between the two receptors.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.