Neuroimaging PheWAS and molecular phenotyping implicate PSMC3 in Alzheimer's disease.

Alzheimers Dement · 2026 · PMC12930104 · PMID 41732108

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

approaches statistical significanceP = 0.051so close (0.05 < p ≤ 0.1)

This increase approaches statistical significance ( P = 0.051).

also in 141 other papers

nominally significantno p-value reported

In addition, we required the nominally significant genetic covariance signals to fall within two megabases upstream and downstream of the corresponding gene (based on genome build 37 coordinates). 2.11 Phenotypic correlation between NIDPs and family history of dementia We assessed the significance of empirical measurement differences in NIDPs across UKB individuals with and without a family history of dementia.

also in 7,732 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.