Reduced serum AHR agonistic activity reflects amyloid dysregulation in AT1 subtypes of Alzheimer's disease.

Alzheimers Res Ther · 2026 · PMC12930576 · PMID 41652618

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hedged sentences

0.0001

closest p · 0.0× alpha

0.1000

boldest claim

The sentences

highly significantp < 0.0001actually significant

For pTau181, we observed highly significant effect modification by amyloid status (interaction β = 0.65, p < 0.0001).

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did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

While the A + group showed a numerically stronger Aβ1–42 effect, the interaction term did not reach statistical significance ( p = 0.10), and both groups showed the same negative direction.

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