The association of first and second-trimester serum biomarkers with adverse perinatal outcomes in late-preterm and term deliveries: a retrospective cohort study.

BMC Pregnancy Childbirth · 2026 · PMC12930652 · PMID 41639641

Europe PMC DOI

hedged sentence

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

a marginal trendp = 0.095so close (0.05 < p ≤ 0.1)

did not reach statistical significancep = 0.095so close (0.05 < p ≤ 0.1)

Although PAPP-A showed a marginal trend toward increased risk of PPROM (aOR = 1.826), this did not reach statistical significance ( p = 0.095).

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