Barely Significant
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The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial.

J Sleep Res · 2026 · PMC12931678 · PMID 40660750

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showed a trendno p-value reported
Daridorexant 50 mg also showed a trend to improved daytime functioning as assessed by the IDSIQ total score and the three IDSIQ domain scores, although the differences to placebo with both daridorexant doses in IDSIQ total score were not significant.

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