Barely Significant
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Topography and cognitive impact of brain iron deposition in cerebral amyloid angiopathy: Evidence from 7T quantitative susceptibility mapping.

Alzheimers Dement · 2026 · PMC12932329 · PMID 41736289

1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

approaching significancep = 0.08so close (0.05 < p ≤ 0.1)
Adding the PVS × CIB interaction term further increased the explained variance to 26.5%, with the interaction approaching significance ( β _std = −0.26, p = 0.08), suggesting that cortical iron may have a more detrimental effect on cognition in individuals with higher PVS burden.

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