Epigenomic subtypes of late-onset Alzheimer's disease reveal distinct microglial signatures.

Acta Neuropathol · 2026 · PMC12932393 · PMID 41733741

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did not reach statistical significanceno p-value reported

Notably, LOAD-S2 displayed a greater overlap with previously reported DMPs from the PFC DNAm meta-analysis (34 CpGs; OR 150.01), whereas the overlap with LOAD-S1 was minimal (one CpG) and did not reach statistical significance (Supplementary Table 13).

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