Hydrocortisone combined with fludrocortisone for treatment of adults with septic shock: an updated meta-analysis and systematic review.

Front Med (Lausanne) · 2026 · PMC12932585 · PMID 41756379

Europe PMC DOI

hedged sentence

0.7900

closest p · 15.8× alpha

0.7900

boldest claim

The sentences

did not reach statistical significancep = 0.79not close (p > 0.1)

In this subgroup, the association between HC + FC and 28-day mortality did not reach statistical significance [RR: 0.99; 95% CI: (0.91, 1.08); p = 0.79].

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