Interaction of CYP2C19 with the effect of clopidogrel in secondary prevention of major ischemic events: Systematic review and meta-analysis.

Int J Stroke · 2026 · PMC12932687 · PMID 40844153

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showed a trendno p-value reported

33 – 36 In our study, non-carriers of the CYP2C19 LoF allele showed a trend of a higher bleeding risk, but the interaction did not show statistical significance when interaction was investigated separately per trial ( Supplementary Figure IV ).

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