Barely Significant
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Lesions involving the insula are associated with reduced appetite and weight loss.

Brain Commun · 2026 · PMC12933212 · PMID 41756215

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The prefrontal cortex and striatum also featured prominently in model, with some qualitative convergent findings in the right ventromedial prefrontal cortex and bilateral striatum which did not reach statistical significance for the weight change sample.

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