Targeted Temperature Management in Cardiogenic Shock Survivors of Cardiac Arrest: A Systematic Review and Meta-Analysis.

Cureus · 2026 · PMC12933357 · PMID 41755969

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showed a trendno p-value reported

Significant heterogeneity was observed (I 2 = 47.9%), driven by a divergence between observational studies, which favored TTM (RR 0.90; 95% CI 0.63-1.27), and RCTs, which showed a trend toward harm or neutrality (RR 1.05; 95% CI 0.86-1.28).

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