Impact of neuromuscular blockade depth on postoperative systemic cytokine release: a systematic review and meta-analysis.

Korean J Anesthesiol · 2026 · PMC12933400 · PMID 41189313

Europe PMC DOI

hedged sentences

0.1290

closest p · 2.6× alpha

0.1290

boldest claim

The sentences

a notable trendP = 0.129not close (p > 0.1)

Additionally, a notable trend was observed, with a higher incidence of POD in the moderate NMB group compared with that in the deep NMB group (moderate NMB: 34.15% vs. deep NMB: 17.07%, P = 0.129).

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did not reach statistical significanceno p-value reported

In summary, only TNF-α levels showed a statistically significant difference immediately postoperatively, while IL-6 levels exhibited a noticeable decreasing tendency in the deep NMB group compared with the moderate NMB group, although the difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.