40 , 63 , 64 ARX PAE COs had significantly fewer PAX6 + cells than controls ( p = 0.0085, d = 0.955; Figures 3F - 3H ) and showed a trend toward decreased HES1 expression ( Figures S19A - S19D ), while HES5 expression trended upward ( Figures S19A - S19D ).
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Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons.
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