Distinct DNA methylation signatures in maternal blood reveal unique immune cell shifts in preeclampsia and the pregnancy-postpartum transition.

Interestingly, during pregnancy, granulocytes showed an increasing trend from the first trimester through delivery, whereas NK cells, B cells, and CD4 + T cells decreased over the same period.

also in 63,971 other papers

While this difference did not reach statistical significance, it aligns with observations that monocyte behaviour in PE may involve functional dysregulation rather than substantial changes in abundance.[ 58 – 62 ] Monocytes are key players in the innate immune system and contribute to tissue remodeling and immune surveillance through their differentiation into macrophages and dendritic cells.

also in 111,027 other papers