Comparison of probiotics to lactulose for minimal hepatic encephalopathy in patients with cirrhosis: a meta-analysis of randomized controlled trials.

Front Med (Lausanne) · 2026 · PMC12936003 · PMID 41767517

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did not reach statistical significanceno p-value reported

Importantly, although the pooled RR for OHE development did not reach statistical significance, the point estimate (RR = 1.38) suggests a potential trend toward higher OHE risk with probiotics.

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