Inflammatory stimulus enhances synaptic material uptake by adult APP microglia in a microfluidic neuron-microglia co-culture model.

J Neuroinflammation · 2026 · PMC12937550 · PMID 41709227

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did not reach statistical significanceno p-value reported

Under basal conditions, APP microglia showed an average ~ 40% higher PSD95 intensity compared to WT; however, this difference did not reach statistical significance and was not interpreted as evidence of increased constitutive synaptic uptake.

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