Genetic, Sociodemographic and Clinical Determinants of COVID-19 Severity in the Republic of Srpska: Exploring Potential Links with Neanderthal-Derived Variants.

Biomedicines · 2026 · PMC12937615 · PMID 41751377

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.8148

boldest claim

The sentences

borderline significancep = 0.050actually significant

29.6%; p = 0.013), while hypercholesterolemia showed borderline significance ( p = 0.050).

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did not reach statistical significancep = 0.8148not close (p > 0.1)

Indeed, the X 2 HWE p values for the rs1156361 and rs35044562 variants did not reach statistical significance in the patient group; these two variants were confirmed to be in HWE (X 2 HWE = 0.0549, p = 0.8148; X 2 HWE = 2.2866, p = 0.1305) ( Supplementary Table S2 ).

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