Extracellular Superoxide Dismutase in Acute Respiratory Distress Syndrome: Pathogenic Mechanisms and Therapeutic Implications.

A similar trend was identified between the E1/I1 mutation and FVC in another study, but it was underpowered and failed to reach significance [ 228 ].

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Of note, patients only received one dose of rhSOD, and illness severity was significantly higher in one experimental group and approached significance in the other compared to placebo [ 197 ].

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