Identification and Functional Validation of PTH2R as a Therapeutic Target in Lung Adenocarcinoma.

Biomedicines · 2026 · PMC12937737 · PMID 41751388

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did not reach statistical significanceno p-value reported

Following melatonin treatment, mRNA levels of ENPP2 ( p < 0.05) and KRT4 were significantly reduced in line with sequencing results, and while KRT4 displayed a downregulation trend consistent with transcriptomic data in our independent validation, this difference did not reach statistical significance due to within-group variation ( Figure 9 A).

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