Barely Significant
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A Developmental Study of MeCP2 with Core and Linker Histones Indicates a Dynamic Change During Adolescent Brain Development in a Region- and Strain-Specific Manner in Mice.

Biomolecules · 2026 · PMC12937746 · PMID 41750404

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In contrast, in the cerebellum of CD1 mice, we observed a trend toward increased H3 levels ( Figure 2 A,A3) between P21 and P56, although this difference did not reach statistical significance.

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an increasing trendno p-value reported
We observed an increasing trend in H3 levels in the cerebellum of CD1 mice using a polyclonal H3 antibody; however, this trend did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.