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Prospective Evaluation of ESBL Risk Factors and Appropriateness of Empirical Therapy in Hospitalized Patients with Community-Onset Pyelonephritis.

Antibiotics (Basel) · 2026 · PMC12937752 · PMID 41750526

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In the multivariate logistic regression analysis, male sex ( p = 0.038) and hospitalization more than one month prior ( p = 0.016) were identified as independent risk factors for ESBL positivity, while prior antibiotic use in the last three months showed a borderline association ( p = 0.055) and did not reach statistical significance.

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