Body-Wide Glycolytic Shift, Oxidative Stress, and Sex-Specific Effect of Caloric Restriction in a Mouse Model of Alzheimer's Disease.

Antioxidants (Basel) · 2026 · PMC12937841 · PMID 41750572

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Compared to WT littermates, AL-fed AD females showed a trend towards reduced activity of GPx and GST and had a significantly (1.6-fold) higher GR, as well as a significantly lower (by 62%) G6PDH activity ( Figure 5 E–H).

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