Therapeutic Efficacy of Floating Electrode-Dielectric Barrier Discharge Plasma in Experimental Periodontitis: A Pilot Study.

Although IL-1β levels were numerically lower by 51% (0.49-fold) in the FE-DBD group, the difference did not reach statistical significance ( p > 0.05).

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Consistently with the premise that increased microbial diversity marks periodontitis progression, the results demonstrated that FE-DBD treatment exhibited a notable decreasing trend in the alpha diversity indices (Richness, Chao1, and Shannon) of the microbial community, whereas these indices showed an increasing trend in the control group.

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No statistically significant differences ( p ≥ 0.05) in the Richness, Shannon, or Chao1 indices were observed between the FE-DBD and control groups at either baseline or two weeks post-treatment, although the p -value for the Richness index approached marginal significance at 0.05 ( Figure 4 ).

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