Clopidogrel use is associated with an increased prevalence of Parkinson's disease, particularly among US adults with diabetes.

When medication duration was grouped into quartiles, although OR values showed an increasing trend in longer duration groups compared to participants with usage < 1 year (Q1), these associations also failed to reach statistical significance (all P > 0.05 ).

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In the analysis encompassing all antiplatelet drugs ( Table S1 ), interaction tests failed to reach statistical significance across all prespecified subgroups (all P for Interaction > 0.05 ).

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