TUBB2A and TM4SF1 Methylation Define Prognostic Subgroups in Adult-Type Diffuse Glioma.

Cancers (Basel) · 2026 · PMC12938886 · PMID 41749891

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did not reach statistical significanceno p-value reported

Although higher expression tended to correlate with poorer outcomes, the association did not reach statistical significance, and other differentially methylated genes (e.g., TGFB2 , CCDC91 , WHSC1 ) showed no survival differences.

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a nonsignificant trendno p-value reported

MBD1 showed a nonsignificant trend toward increased expression, while MBD3 and DNMT3A did not display subtype-specific differences.

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