Tumor-Derived LIF Promotes GDF15-Driven Cachexia and Adverse Outcomes in Gastric Cancer.

Cells · 2026 · PMC12938927 · PMID 41744798

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showed a trendno p-value reported

Notably, although not reaching statistical significance, higher LIF expression showed a trend toward poorer overall survival, as illustrated in Supplementary Figure S1 , suggesting distinct but potentially converging roles of LIF and GDF15 in the cachexia phenotype.

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