Barely Significant
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COMBI-EU: Real-World Evidence on Adverse Event Management and Time on Therapy with Adjuvant Dabrafenib Plus Trametinib in Patients with BRAF V600-Mutant Melanoma.

Cancers (Basel) · 2026 · PMC12939694 · PMID 41749920

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showed a trendno p-value reported
High-level treatment-related adverse event management showed a trend toward improved treatment adherence (HR: 0.74; [0.49–1.14]), which was statistically significant for pyrexia.

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