Barely Significant
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Nonsense Mutation in <i>USH2A</i> Exon-13 Activates the Innate Immune Response in Müller Glial Cells.

Int J Mol Sci · 2026 · PMC12940303 · PMID 41751772

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Despite the average ciliary length being significantly increased in two 13KO subclones, this did not reach statistical significance in the comparison of the 13KO pool to the ISO-CTRL.

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highly significantno p-value reported
Surprisingly, terms in the first three categories reached highly significant adjusted p -values, with peaks of 10 −55 , indicating an unexpected major phenotype in the MGCs caused by the USH2A 13KO mutation.

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