As shown in the rhythm analysis in Figure 3 A, Adh1 ( p Cycle = 0.005), Cyp2e1 ( p Cycle = 0.023), and Aldh2 ( p Cycle = 0.037) exhibited significant rhythmicity prior to SD (Day 0–1), whereas Aldh1b1 (( p Cycle = 0.486) did not reach statistical significance.
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Diurnal Regulation and Gene-Specific Vulnerability of Oxidative Alcohol-Metabolizing Enzymes to Circadian Disruption.
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