Barely Significant
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Enzyme Catalytic Parameters and Evolution Across the Dissipation Plane.

Int J Mol Sci · 2026 · PMC12940570 · PMID 41751846

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a clear trendno p-value reported
It survived the eons of biological evolution and exhibits a clear trend: more evolved members of the same enzyme family are associated with greater specificity toward their substrate and higher entropy production [ 2 , 134 ].

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