Myocardial Matrix Metalloproteinase 3 Protein Expression in Ischemic Heart Failure.

Int J Mol Sci · 2026 · PMC12940760 · PMID 41751834

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0540

boldest claim

The sentences

highly significantp < 0.001actually significant

In contrast, stage B HF patients exhibited a highly significant increase in MMP3 staining score compared to controls ( p < 0.001).

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did not reach statistical significancep > 0.05actually significant

However, this difference did not reach statistical significance when compared to 5A/6A heterozygotes and 6A homozygotes ( p > 0.05, Figure 4 C).

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borderline significantp = 0.054so close (0.05 < p ≤ 0.1)

Model 1 revealed that the number of 5A alleles was significantly associated with elevated MMP-3 expression in non-cardiomyocytes ( p < 0.05), whereas the association in cardiomyocytes was borderline significant ( p = 0.054).

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