Barely Significant
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Integrating Bidirectional Mendelian Randomization with Multi-Omics Reveals Causal Serum Metabolites and Novel Metabolic Drivers of Multiple Myeloma.

Int J Mol Sci · 2026 · PMC12941277 · PMID 41752037

Europe PMCDOI
2
hedged sentences
0.0163
closest p · 0.3× alpha
0.0163
boldest claim

The sentences

nominally significantp -value = 0.0163actually significant
A complex pattern emerged for Dimethylarginine (SDMA + ADMA) and glutaroyl carnitine: IVW analysis showed nominally significant reverse associations ( p -value = 0.0163 and 0.0276), but Steiger tests strongly rejected the reverse direction ( p -value = 0.0011 and 0.0021).

also in 7,732 other papers

borderline significanceno p-value reported
Six additional pathways showed borderline significance ( p -values: 0.0791–0.1196).

also in 7,017 other papers

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