Reply to Wostyn, P.; Nedergaard, M. Ocular Glymphatic Dysfunction as a Potential Link Between Obstructive Sleep Apnea and Retinal Structural Changes. Comment on "Pusic Sesar et al. Multimodal Assessment of Ocular Parameters in Patients with Severe Obstructive Sleep Apnea with Emphasis on Retinal Structural Changes. <i>Life</i> 2025, <i>15</i>, 1307".

Life (Basel) · 2026 · PMC12941844 · PMID 41752853

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did not reach statistical significanceno p-value reported

In our study, we observed significant thinning of the ganglion cell layer (GCL) in patients with severe obstructive sleep apnea (OSA) compared with healthy controls, along with a trend toward reduced retinal nerve fiber layer (RNFL) thickness that did not reach statistical significance.

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