Sperm DNA Fragmentation Is Associated with Impaired Directional Motility and Kinematic Efficiency: A CASA-Based Study.

Medicina (Kaunas) · 2026 · PMC12943575 · PMID 41752775

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did not reach statistical significanceno p-value reported

Sperm DNA fragmentation showed a significant negative correlation with straight-line velocity (VSL), whereas correlations with linearity-related indices (LIN, STR, and WOB) were negative but did not reach statistical significance, indicating that increasing DNA fragmentation primarily affects forward progression rather than overall trajectory linearity.

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