Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial<sup>®</sup> Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial.

Pharmaceutics · 2026 · PMC12944164 · PMID 41754978

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did not reach statistical significanceno p-value reported

However, statistically significant differences were detected only for the comparison between 24 h and 2 weeks (FDR-adjusted p = 0.019), while the remaining comparisons did not reach statistical significance, indicating the absence of a consistent or progressive temporal trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial&lt;sup&gt;®&lt;/sup&gt; Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial.

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Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial<sup>®</sup> Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial.